MSH5 Pre-design Chimera RNAi
产品名称： MSH5 Pre-design Chimera RNAi
英文名称： MSH5 Pre-design Chimera RNAi
产品编号： H00004439-R04
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens mutS homolog 5 (E. coli) (MSH5), transcript variant 4, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_172166
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4439
- Gene Name:
- MSH5
- Gene Alias:
- DKFZp434C1615,G7,MGC2939,MutSH5,NG23
- Gene Description:
- mutS homolog 5 (E. coli)
- Omim ID:
- 603382
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. Alternative splicing results in four transcript variants encoding three different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000029187,OTTHUMP00000029188,mutS homolog 5
- Related Disease
- Abortion, Spontaneous
- Arthritis, Rheumatoid
- Azoospermia
- Breast cancer
- Carcinoma, Non-Small-Cell Lung
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- IgA Deficiency
- Infertility, Male
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Meningeal Neoplasms
- Meningioma
- Obesity
- Oligospermia
- Ovarian Failure, Premature
- Werner syndrome