FITC标记的脑特异性跨膜蛋白抗体
产品名称： FITC标记的脑特异性跨膜蛋白抗体
英文名称： Anti-NETO2/FITC
产品编号： HZ-11896R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NETO2/FITC Conjugated antibody
FITC标记的脑特异性跨膜蛋白抗体
| 英文名称 | Anti-NETO2/FITC |
| 中文名称 | FITC标记的脑特异性跨膜蛋白抗体 |
| 别 名 | Brain specific transmembrane protein; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2; BTCL2; FLJ10430; FLJ14724; FLJ90456; NEOT2; NETO 2; Neto2; NETO2_HUMAN; Neuropilin (NRP) and tolloid (TLL) like 2; Neuropilin and tolloid like protein 2; Neuropilin and tolloid-like protein 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 通道蛋白 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NETO2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] Function: Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission. Subunit: Interacts with GRIK2 and GRIK3, but neither with AMPA-nor with NMDA-sensitive glutamate receptors Subcellular Location: Membrane. Post-translational modifications: N-glycosylated. Similarity: Contains 2 CUB domains. Contains 1 LDL-receptor class A domain. Database links: Entrez Gene: 81831 Human Entrez Gene: 74513 Mouse Entrez Gene: 307757 Rat Omim: 607974 Human SwissProt: Q8NC67 Human SwissProt: Q8BNJ6 Mouse SwissProt: C6K2K4 Rat Unigene: 444046 Human Unigene: 126079 Mouse Unigene: 222298 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一个预测跨膜蛋白，包含两个胞外CUB结构域，接着是低密度脂蛋白A类（LDLa）结构域。大鼠中的一个类似基因编码一种蛋白质，通过调节红藻氨酸受体功能调节大脑谷氨酸信号。该基因的表达可能是婴儿血管瘤增殖的生物标志物。该基因的假基因位于8号染色体的长臂上。另一种编码多个异构体的剪接转录变体已被观察到该基因。[ RefSeq，2011月1日]