EPO (human):Fc (human) (rec.) (non-lytic)
产品名称: EPO (human):Fc (human) (rec.) (non-lytic)
英文名称:
产品编号: CHI-HF-220EPO
产品价格: 0
产品产地: USA
品牌商标: chimerigen
更新时间: null
使用范围: null
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Synonyms : EPO Host : CHO cell Sequence : The extracellular domain of human EPO(NP_000790.2)(Pro30-Arg193) is fused to the N-terminus of the Fc region of a mutant human IgG1. Molecular Mass : 48 KDa (monomer) Non-lytic : Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC). Purity : >98%,by SDS-PAGE under reducing conditions Endotoxin Content : <0.06 EU/μg as determined by LAL test. Activity: Measured by the dose-dependant stimulation of human megakaryoblastic leukemia cells. Formulation : Lyophilized from 0.2 μm-filtered solution in PBS. Reconstitution : Reconstitute at 100 μg/ml in sterile PBS. Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. Avoid freeze/thaw cycles.