CDK7 monoclonal antibody, clone 45H1
产品名称： CDK7 monoclonal antibody, clone 45H1
英文名称： CDK7 monoclonal antibody, clone 45H1
产品编号： MAB0831
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CDK7.
- Immunogen:
- Recombinant His/ABD fusion protein corresponding to amino acids 136-346 of human CDK7.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 0.5 mg/mL
- Isotype:
- IgG2b, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:2000-1:5000)
Immunoprecipitation (1 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Secrets of a double agent: CDK7 in cell-cycle control and transcription.
Fisher RP.J Cell Sci. 2005 Nov 15;118(Pt 22):5171-80.
- 2.
- Cell cycle control of embryonic stem cells.
White J, Dalton S.Stem Cell Rev. 2005;1(2):131-8.
- 3.
- Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control?
Nigg EA.Curr Opin Cell Biol. 1996 Jun;8(3):312-7.
- Entrez GeneID:
- 1022
- Gene Name:
- CDK7
- Gene Alias:
- CAK1,CDKN7,MO15,STK1,p39MO15
- Gene Description:
- cyclin-dependent kinase 7
- Omim ID:
- 601955
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq
- Other Designations:
- 39 KDa protein kinase,Cdk-activating kinase,cell division protein kinase 7,cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase),homolog of Xenopus MO15 Cdk-activating kinase,kinase subunit of CAK,serine/threonine kinase stk1,ser
- Interactome
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Colonic Neoplasms
- Colorectal Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lung Neoplasms
- Multiple Sclerosis
- Ovarian Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Rectal Neoplasms
- Urinary Bladder Neoplasms
- Werner syndrome