FITC标记的S期细胞周期相关蛋白抗体
产品名称： FITC标记的S期细胞周期相关蛋白抗体
英文名称： Anti-SPHAR/FITC
产品编号： HZ-17658R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SPHAR/FITC Conjugated antibody
FITC标记的S期细胞周期相关蛋白抗体
| 英文名称 | Anti-SPHAR/FITC |
| 中文名称 | FITC标记的S期细胞周期相关蛋白抗体 |
| 别 名 | S phase response (cyclin-related) |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 8kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPHAR |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SPHAR is a 63 amino acid protein that belongs to the cyclin family. The SPHAR gene contains 1,120 base pairs and is located on human chromosome 1q42.13. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Database links: Entrez Gene: 10638 Human SwissProt: Q15513 Human SwissProt: Q6NSB9 Human Unigene: 511754 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
SPHAR是属于细胞周期蛋白家族的63个氨基酸。SPHAR基因含有1120个碱基对，位于人类染色体1q42.13。第1号染色体是最大的人类染色体，跨越2亿6000万个碱基对，占人类基因组的8%。1号染色体上约有3000个基因，考虑到基因数量众多，还有大量与1号染色体相关的疾病。值得注意的是，罕见的老化性疾病Hutchinson-Gilford progeria与编码层粘连蛋白A的LMNA基因有关。当有缺陷时，LMNA基因产物可在细胞核内积聚并引起特征性核小泡。MutyH基因位于1号染色体上，是家族性腺瘤性息肉病的部分原因。Stutkle综合征、帕金森病、高雪氏病和Aukes综合征也与1号染色体有关。