FITC标记的TNF家族B细胞激活因子抗体
产品名称： FITC标记的TNF家族B细胞激活因子抗体
英文名称： Anti-BAFF/FITC
产品编号： HZ-2431R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 IF=1:50-200
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Rabbit Anti-BAFF/FITC Conjugated antibody
FITC标记的TNF家族B细胞激活因子抗体
| 英文名称 | Anti-BAFF/FITC |
| 中文名称 | FITC标记的TNF家族B细胞激活因子抗体 |
| 别 名 | ApoL related ligand TALL 1; B cell Activating Factor; B lymphocyte stimulator ; BLYS; CD 257; CD257; CD257 antigen; delta BAFF; Dendritic cell derived TNF like molecule; DTL; DTL precursor; TALL 1; TALL1; THANK; TNF and APOL related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNF homolog that activates apoptosis NKFB and JNK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 20; Tumor necrosis factor like protein ZTNF4; Tumor necrosis factor superfamily member 13B; ZTNF4; TN13B_MOUSE . |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 生长因子和激素 激酶和磷酸酶 细胞分化 b-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, |
| 产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse BAFF |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq]. Function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Subunit: Belongs to the tumor necrosis factor family. Subcellular Location: Secreted and Cell membrane. Tissue Specificity: Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Post-translational modifications: The soluble form derives from the membrane form by proteolytic processing. Isoform 2 is not efficiently shed from the membrane unlike isoform 1. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 10673 Human Entrez Gene: 24099 Mouse Omim: 603969 Human SwissProt: Q9Y275 Human SwissProt: Q9WU72 Mouse Unigene: 525157 Human Unigene: 596110 Human Unigene: 28835 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是属于肿瘤坏死因子（TNF）配体家族的细胞因子。该细胞因子是受体TNFRSF13B/TACI、TNFRSF17/BCMA和TNFRSF13C/BAFFR的配体。这种细胞因子在B细胞谱系细胞中表达，并作为强有力的B细胞激活剂发挥作用。它还显示出在B细胞的增殖和分化中起重要作用。[由RefSeq提供]。