FITC标记的液泡蛋白分选蛋白26抗体
产品名称： FITC标记的液泡蛋白分选蛋白26抗体
英文名称： Anti-VPS26/FITC
产品编号： HZ-12768R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-VPS26/FITC Conjugated antibody
| FITC标记的液泡蛋白分选蛋白26抗体 |
| 英文名称 | Anti-VPS26/FITC |
| 中文名称 | FITC标记的液泡蛋白分选蛋白26抗体 |
| 别 名 | FLJ12930; HB 58; HB58; Hbeta 58; Hbeta 58 homolog; Hbeta58; Hbeta58 homolog; hVPS 26; hVPS26; MGC94168; PEP 8A; PEP8A; Vacuolar protein sorting 26 A; Vacuolar protein sorting 26; Vacuolar protein sorting 26 homolog A; Vacuolar protein sorting 26 homolog A S. pombe; Vacuolar protein sorting 26 homolog A yeast; Vacuolar protein sorting 26 yeast; Vacuolar protein sorting 26 yeast homolog; Vacuolar protein sorting 26A; Vacuolar protein sorting associated protein 26A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26; Vesicle protein sorting 26A; VP26A_HUMAN; VPS 26; VPS 26A; VPS26A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VPS26 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Subcellular Location: Cytoplasm. Endosome membrane. Similarity: Belongs to the VPS26 family. Database links: Entrez Gene: 9559 Human Entrez Gene: 30930 Mouse Entrez Gene: 361846 Rat Omim: 605506 Human SwissProt: O75436 Human SwissProt: P40336 Mouse SwissProt: Q6AY86 Rat Unigene: 499925 Human Unigene: 260703 Mouse Unigene: 473468 Mouse Unigene: 3673 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
该基因属于一组空泡蛋白分选（VPS）基因。编码蛋白是大型多聚体复合物（称为回旋体复合物）的组成部分，参与蛋白质从内体逆行传输到反式高尔基体网络。组成这个复合体的酵母和人类蛋白质之间的结构相似性暗示了功能的相似性。酵母和哺乳动物细胞中的表达研究表明，该蛋白与VPS35直接相互作用，VPS35是反转录复合物的核心。选择性剪接导致编码不同异构体的多个转录体变体。