Synonyms : BMP2; Bone Morphogenetic Protein 2
Host : CHO cell
Sequence : The extracellular domain of human BMP-2 (NP_001191.1) (Arg289-Arg396) is fused to the N-terminus of the Fc region of a mutant human IgG1.
Molecular Mass : 42 KDa (monomer)
Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
Purity : >98%，by SDS-PAGE under reducing conditions.
Endotoxin Content : <0.06 EU/μg as determined by LAL test.

Activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
Formulation : Lyophilized from 0.2μm-filtered solution in PBS.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Avoid freeze/thaw cycles.