赖氨酸，天冬氨酸，谷氨酸，亮氨酸相关序列抗体
产品名称： 赖氨酸，天冬氨酸，谷氨酸，亮氨酸相关序列抗体
英文名称： KDEL
产品编号： bs-6940R
产品价格： null
产品产地： 北京
品牌商标： BIOSS
更新时间： 2025-11-06T11:17:45
使用范围： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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Endoplasmic reticulum Marker.
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.