重组SARS-CoV-2 N蛋白(His标签)

中文名称：重组SARS-CoV-2 N蛋白(His标签)
英文名称：Recombinant SARS-CoV-2 Nucleocapsid Protein (N-6His)
产品规格：1mg
本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 Nucleocapsid蛋白(Met1-Ala419)，N端带有一个6*his标签，用作免疫原或标准品。

技术指标：
Accession#：QHD43423.2
分子量：49.4kDa
实测分子量：50-60kDa（还原条件下）
纯度：＞95%（还原性SDS-PAGE）
纯化方式：亲和色谱法
贮存液：20mM Tris-HCl,300mM NaCl,1mM EDTA,pH8.0，0.2μm过滤
保存条件：-20℃。

生物活性：

Immobilized SARS-CoV-2 NP Antibody (Cat#JN4027) at 5μg/ml (100μl/well) can bind SARS-CoV-2 Nucleocapsid Protein-His(Cat#JN2081).
The ED₅₀ of Recombinant SARS-CoV-2 Nucleocapsid Protein-His(Cat#JN2081) is 68ng/ml.

批稳定性：

Batch stability is con?rmed by binding ability with SARS-CoV-2 NP Antibody (Cat#JN4027)
The result showed that the batch variation is no signi?cant di?erences among these samples.

背景资料：
Coronavirus N protein is required for coronavirus RNA synthesis,and has RNA chaperone activity that may be involved in template switch.Nucleocapsid protein is a most abundant protein of coronavirus.N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.Because of the conservation of N protein sequence and its strong immunogenicity,the N protein of coronavirus is chosen as a diagnostic tool. 

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