重组人SHMT1(胞质丝氨酸羟甲基转移酶)

中文名称：重组人SHMT1(胞质丝氨酸羟甲基转移酶)
英文名称：Recombinant Human Serine Hydroxymethyltransferase Cytosolic
产品规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met3-Phe483在C端含有His标签。

SHMT1质量控制：＞95%(还原性SDS-PAGE)

SHMT1制剂：冻干品

SHMT1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SHMT1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SHMT1：
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome. 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！