PODS® Human BDNF 脑源性神经营养因子-细胞/细菌培养-试剂-生物在线
上海逍鹏生物科技有限公司
PODS® Human BDNF 脑源性神经营养因子

PODS® Human BDNF 脑源性神经营养因子

商家询价

产品名称： PODS® Human BDNF 脑源性神经营养因子

英文名称： PODS® Human BDNF (Brain-derived neurotrophic factor)

产品编号： PPH1

产品价格： 0

产品产地： 英国

品牌商标： Cell Guidance Systems

更新时间： null

使用范围： null

上海逍鹏生物科技有限公司
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PODS® Human BDNF

                         
PODS® co-crystals  PODS® co-crystals 

 

CellGS Catalogue Code       

Product Name                

Pack Size             

    

PPH1-50                

PODS Human BDNF                 

50 million            

          

PPH1-250                

PODS Human BDNF                 

250 million          

             

PPH1-1000                

PODS Human BDNF                 

1 billion           

          

 

PODS 技术

将生长因子包埋进蛋白质晶体（多角体蛋白）中，多角体蛋白能够保护包埋的生长因子，并维持其稳定性与生物活性，进而持续释放到细胞培养系统中。

 

 

PODS BDNF 描述

PODS多角体蛋白与BDNF共结晶。BDNF(Brain-derived neurotrophic factor, 脑源性神经营养因子)是一种神经生长因子，它与低亲和力神经生长因子受体(LNGFR)和原肌球蛋白受体激酶B (TrkB)结合，支持神经元生长和存活。海马区BDNF(Brain-derived neurotrophic factor, 脑源性神经营养因子)的表达对长期记忆的储存和学习至关重要。BDNF(Brain-derived neurotrophic factor, 脑源性神经营养因子)的某些蛋白结构域与NGF和另一种神经营养因子NT-3(神经营养因子-3)的结构域相同。人、小鼠、大鼠和猪BDNF(脑源性神经营养因子)是交叉反应的。

 

PODS BDNF 规格

 

PODS BDNF Product   Details                

Length                

164 aa                

Molecular   Weight      

37.6 kDa                

Structure                

Dimer                

Source                

Spodoptera   frugiperda (Sf9) cell culture                

Accession   Number     

P23560                

Endotoxin   Level       

<0.06 EU/ml   as measured by gel clot LAL assay                

Formulation                

PODS® were   lyophilized from a volatile solution                

Reconstitution                

PODS®   co-crystals may be reconstituted at 200 million co-crystals/ml in water. 20%   glucose has a buoyant density closer to PODS® co-crystals and can be useful   for aliquoting.                

PODS®   co-crystals are highly stable when stored in aqueous solution (pH range 6 -   8).                

Stability and   Storage 

Upon receipt,   store at 4°C. PODS® co-crystals are stable for at least 1 year when dry and 6   months when resuspended.                

 

PODS BDNF 使用建议

PODS® co-crystals provide a depot of proteins which are steadily secreted. It has been estimated that the biological activity of 50 million PODS® co-crystals generates the same peak dose as 3.3 μg of standard recombinant protein. However, at 5 days following the start of seeding the PODS® co-crystals, there are more than 50% of these peak levels still present in the culture system. Ultimately, the amount of PODS® co-crystals that is optimal for a particular experiment should be determined empirically. Based on previous data, we suggest using 50 million PODS® co-crystals in place of 3.3 μg of standard growth factor as a starting point."

To control for cross-reactivity with cells or as a negative control, we recommend using PODS® growth factors alongside PODS® Empty crystals, as the latter do not contain or release cargo protein.

 

PODS BDNF AA Sequence

MADVAGTSNR DFRGREQRLF NSEQYNYNNS KNSRPSTSLY KKAGLMHSDP ARRGELSVCD SISEWVTAAD KKTAVDMSGG TVTVLEKVPV SKGQLKQYFY ETKCNPMGYT KEGCRGIDKR HWNSQCRTTQ SYVRALTMDS KKRIGWRFIR IDTSCVCTLT IKRGR

 

PODS BDNF Alternative Names

Brain-derived neurotrophic factor, neurotrophin, abrineurin, 脑源性神经营养因子

 

PODS BDNF 文件资料

PPH1 Datasheet             PODS User Guide             PODS MSDS            

 

更多PODS 相关产品：PODS 生长因子

 

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