FITC标记的血小板白细胞C激酶底物同源结构域M2抗体
产品名称： FITC标记的血小板白细胞C激酶底物同源结构域M2抗体
英文名称： Anti-PLEKHM2/FITC
产品编号： HZ-8063R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-PLEKHM2/FITC Conjugated antibody
FITC标记的血小板白细胞C激酶底物同源结构域M2抗体
| 英文名称 | Anti-PLEKHM2/FITC |
| 中文名称 | FITC标记的血小板白细胞C激酶底物同源结构域M2抗体 |
| 别 名 | PH domain containing family M member 2; Pleckstrin homology domain containing family M (with RUN domain) member 2; Pleckstrin homology domain containing family M member 2; PLEKHM 2; RP11 169K16.1; Salmonella induced filaments A and kinesin interacting protein; SifA (Salmonella induced filaments A) and kinesin interacting protein; SifA and kinesin interacting protein; SKIP; KIAA0842; Novel RUN and PH domain containing protein; PKHM2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 113kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PLEKHM2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo. Function: May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation. Subunit: Interacts with KIF5B. Interacts with the S.typhimurium sifA protein; required for S.typhimurium infection. Subcellular Location: Cytoplasm. Similarity: Contains 1 PH domain. Contains 1 RUN domain. Database links: UniProtKB/Swiss-Prot: Q8IWE5.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
PykHM2，也被称为Skip，是Prkkestin同源结构域M蛋白家族的成员。虽然PelkHM2知之甚少，但最近在人类造血干细胞中检测差异基因表达的研究表明它在干细胞中特异性表达，提示PYKHM2可能在红系的承诺和发育中起作用。其他研究表明，PulkHM2与沙门氏菌毒力因子SIFA的相互作用需要沙门氏菌致病性，提示PYKHM2除了发育中的胚胎以外，还具有细胞作用。