IL1RAPL1 Pre-design Chimera RNAi
产品名称： IL1RAPL1 Pre-design Chimera RNAi
英文名称： IL1RAPL1 Pre-design Chimera RNAi
产品编号： H00011141-R02
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
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- Specification
- Product Description:
- Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_014271
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 11141
- Gene Name:
- IL1RAPL1
- Gene Alias:
- IL1R8,IL1RAPL,MRX10,MRX21,MRX34,OPHN4,TIGIRR-2
- Gene Description:
- interleukin 1 receptor accessory protein-like 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023097,X-linked interleukin-1 receptor accessory protein-like 1,interleukin 1 receptor-8,mental retardation, X-linked 10,oligophrenin-4,three immunoglobulin domain-containing IL-1 receptor-related 2
- Related Disease
- Autistic Disorder
- Avoidance Learning
- Cardiovascular Diseases
- Chorioamnionitis
- Cognition
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Intelligence Tests
- Memory
- Mental Retardation
- Obstetric Labor, Premature
- Pre-Eclampsia
- Premature Birth
- Psychotic Disorders
- Schizophrenia