FITC标记的Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体
产品名称： FITC标记的Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体
英文名称： Anti-RASGRP3/FITC
产品编号： HZ-19736R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RASGRP3/FITC Conjugated antibody
FITC标记的Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体
| 英文名称 | Anti-RASGRP3/FITC |
| 中文名称 | FITC标记的Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体 |
| 别 名 | Calcium and DAG-regulated guanine nucleotide exchange factor III; Grp3; GRP3_HUMAN; Guanine nucleotide exchange factor for Rap1; Kiaa0846; RAS guanyl releasing protein 3 (calcium and DAG regulated); RAS guanyl releasing protein 3 calcium and DAG regualated guanine nucleotide exchange factor iii; Ras guanyl-releasing protein 3; RASGRP3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 78kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RASGRP3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] Function: Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Similarity: Belongs to the RASGRP family. Contains 2 EF-hand domains. Contains 1 N-terminal Ras-GEF domain. Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Ras-GEF domain. Database links: Entrez Gene: 25780 Human Entrez Gene: 240168 Mouse Omim: 609531 Human SwissProt: Q8IV61 Human Unigene: 143674 Human Unigene: 329203 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
成员的Ras（HRAS；国有企业；我190020）函数在信号转导分子GTP酶GTP / GDP的失活，调节开关周期之间的GDP和GTP结合活性的状态。鸟嘌呤核苷酸交换因子（FS），如rasgrp3 Ras活化剂，是由收购的刺激GTP GTP结合，以维持的状态和重点之间的联系是细胞表面受体和RAS的激活（rebhun等人。，2000年10934204 ] [ PubMed提供的（OMIM）。2008年，海