FITC标记的电压门控钾通道亚基Kv8.1抗体
产品名称： FITC标记的电压门控钾通道亚基Kv8.1抗体
英文名称： Anti-KCNV1/FITC
产品编号： HZ-16920R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KCNV1/FITC Conjugated antibody
FITC标记的电压门控钾通道亚基Kv8.1抗体
| 英文名称 | Anti-KCNV1/FITC |
| 中文名称 | FITC标记的电压门控钾通道亚基Kv8.1抗体 |
| 别 名 | KCNV1; KCNV1_HUMAN; Neuronal potassium channel alpha subunit HNKA; Potassium voltage gated channel subfamily V member 1; Potassium voltage-gated channel subfamily V member 1; Voltage gated potassium channel subunit Kv8.1; Voltage-gated potassium channel subunit Kv8.1 |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types. [provided by RefSeq, Jul 2008] Function: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. Subcellular Location: Cell membrane. Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2. Tissue Specificity: Detected in brain. Post-translational modifications: Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. Similarity: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily. Database links: Entrez Gene: 27012 Human Entrez Gene: 505732 Cow Entrez Gene: 67498 Mouse Entrez Gene: 60326 Rat Omim: 608164 Human SwissProt: Q0P583 Cow SwissProt: Q6PIU1 Human SwissProt: Q8BZN2 Mouse SwissProt: P97557 Rat Unigene: 13285 Human Unigene: 300079 Mouse Unigene: 42920 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
电压门控钾（Kv）通道从功能和结构的角度代表了最复杂的电压门控离子通道。它们的多种功能包括调节神经递质释放、心率、胰岛素分泌、神经元兴奋性、上皮电解质转运、平滑肌收缩和细胞体积。该基因编码钾电压门控通道亚家族V的成员。该蛋白主要存在于大脑中，其作用可能是抑制特定类型的外向整流钾通道的功能。[ RefSeq，JUL 2008 ]