Mouse MAb to KSHV/HHV-8 ORF 59
产品名称： Mouse MAb to KSHV/HHV-8 ORF 59
英文名称： Mouse MAb to KSHV/HHV-8 ORF 59
产品编号： Mouse MAb to KSHV/HHV-8 ORF 59
产品价格： 0
产品产地： 美国
品牌商标：
更新时间： 2023-09-19T20:51:30
使用范围： null
Description(名称）
Mouse MAb to KSHV/HHV-8 ORF 59
Catalog #（货号）
13-211-100
Size（规格）
100 µg
Price（价格）
请联系：0769-2289-0558， 0769-22890598， QQ:2533190771
Mouse monoclonal antibody to lytic cycle-associated early protein (50 kDa), encoded by ORF 59 of Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. It is identified as DNA polymerase processivity factor. This antibody originates from ascites fluid and is purified by protein G chromatography.
Details（注意事项）:
Shipping and Storage: This product is shipped frozen on dry ice. Store at -20°C upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
Recommendations: Upon thawing, centrifuge the vial for a few seconds to remove residual droplets from the lid.
Safe Handling Recommendation: This biological preparation should be handled in accordance with biosafety guidelines defined in the BMBL, NIH-CDC HHS Publication No. 93-8395.
FAQ（常见问题）:
How are ABI’s Antibodies supplied? All ABI antibodies are supplied frozen.
How should I store ABI’s Antibodies? We recommend that all antibodies be aliquoted into single-use size portions and stored frozen at -20° C or below. Avoid multiple freeze-thaw cycles as this will affect antibody activity. Do not dilute and freeze – make final dilution just prior to use.
Will ABI’s Antibodies work in Western blot? Not all ABI antibodies work in Western blot. Please see the Certificate of Analysis for each antibody to determine its suitability for Western blot use.
Applications for use（适用范围）:
- ELISA
- Western blot
- Dot blot
- IFA
- Other Protein-Based Assays
- IHC/ICC
- Flow Cytometry
- Antigen Detection
Quality control testing includes（质量控制检测包括）:
- IFA
- SDS-PAGE
- Protein Concentration
Certificate of Analysis（分析报告）:
Reference Articles（已发表参考文献）:
Di Bartolo DL, Hyjek E, Keller S, et al. “Role of Defective Oct-2 and OCA-B Expression in Immunoglobulin Production and Kaposi’s Sarcoma-Associated Herpesvirus Lytic Reactivation in Primary Effusion Lymphoma.” Journal of Virology. 2009;83(9):4308-4315.
Majerciak V, Uranishi H, Kruhlak M, et al. “Kaposi sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 promoting viral ORF59 expression.” Journal of Virology. 2010;85:1528-1540.
Rappocciolo G, Hensler HR, Jais M, et al. “Human Herpesvirus 8 Infects and Replicates in Primary Cultures of Activated B Lymphocytes through DC-SIGN.” J. Virol.. 2008;82:4793-4806. Abstract
Morris VA, Punjabi AS, Lagunoff M. “Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells.” Journal of Virology. 2008;82(17).
“Persistent Activation of STAT3 by Latent Kaposi’s Sarcoma-Associated Herpesvirus Infection of Endothelial Cells.” Journal of Virology. 2007;81(5).
Majerciak V, Pripuzova N, McCoy PJ, Gao S-J, Zheng Z-M. “Targeted Disruption of Kaposi’s Sarcoma-Associated Herpesvirus ORF57 in the Viral Genome Is Detrimental for the Expression of ORF59, K8-alpha, and K8.1 and the Production of Infectious Virus.” Journal of Virology. 2007;81(3).
Zeng Y, Zhang X, Huang Z, et al. “Intracellular Tat of Human Immunodeficiency Virus Type 1 Activates Lytic Cycle Replication of Kaposi’s Sarcoma-Associated Herpesvirus: Role of JAK/STAT Signaling.” Journal of Virology. 2007;81(5):2401-2417.
Xu Y, AuCoin DP, Huete AR, Cei SA, Hanson LJ, Pari GS. “A Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50 Deletion Mutant Is Defective for Reactivation of Latent Virus and DNA Replication.” Journal of Virology. 2005;79(6).
Masood R, Xia G, Smith LD, et al. “Ephrin B2 expression in Kaposi sarcoma is induced by human herpesvirus type 8: phenotype switch from venous to arterial endothelium.” Blood. 2005;105(3).
Klass CM. “The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.” Blood. 2005;105(10):4028-4034.
Pozharskaya VP, Weakland LL, Zimring JC, et al. “Short Duration of Elevated vIRF-1 Expression during Lytic Replication of Human Herpesvirus 8 Limits Its Ability To Block Antiviral Responses Induced by Alpha Interferon in BCBL-1 Cells.” Journal of Virology. 2004;78(12).
Krug LT, Pozharskaya VP, Yu Y, Inoue N, Offermann MK. “Inhibition of Infection and Replication of Human Herpesvirus 8 in Microvascular Endothelial Cells by Alpha Interferon and Phosphonoformic Acid.” Journal of Virology. 2004;78(15):8359-8371.
Webster-Cyriaque J. “Development of Kaposi’s Sarcoma in a Surgical Wound.” The New England Journal of Medicine. 2002;346.