FITC标记的转录辅助因子退变样蛋白3抗体
产品名称： FITC标记的转录辅助因子退变样蛋白3抗体
英文名称： Anti-VGLL3/FITC
产品编号： HZ-9184R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-VGLL3/FITC Conjugated antibody
FITC标记的转录辅助因子退变样蛋白3抗体
| 产品编号 | bs-9184R-FITC |
| 英文名称 | Anti-VGLL3/FITC |
| 中文名称 | FITC标记的转录辅助因子退变样蛋白3抗体 |
| 别 名 | Colon carcinoma related protein; Vestigial like 3 (Drosophila); VGL 3; VGL-3; VGL3; VGLL3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VGLL3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-3 (vestigial-like protein 3), also known as colon carcinoma related protein, is a 326 amino acid nuclear protein that may act as a specific coactivator for the mammalian transcription elongation factors. Both Vgl-1 and Vgl-3 are enriched in placenta, whereas Vgl-2 is expressed in differentiating somites and branchial arches during embryogenesis and is skeletal-muscle specific in adult tissues. There are two isoforms of Vgl-3 that are produced as a result of alternative splicing events. Function: May act as a specific coactivator for the mammalian TEFs Subcellular Location: Nucleus Tissue Specificity: Enriched in placenta. Similarity: Belongs to the vestigial family. Database links: Entrez Gene: 389136 Human Entrez Gene: 73569 Mouse Omim: 609980 Human SwissProt: A8MV65 Human SwissProt: P85442 Mouse Unigene: 714347 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
转录增强因子-1（TEF-1）家族转录因子调节肌肉和胎盘组织特异性基因表达。TEF-1赋予组织特异性的机制在很大程度上取决于TEF-1与组织特异性辅因子的相互作用。转录辅因子VGL-3（残遗样蛋白3），也称为结肠癌相关蛋白，是一种326氨基酸核蛋白，可作为哺乳动物转录延伸因子的特异性共激活因子。VGL-1和VGL-3在胎盘中富集，而VGL-2在胚胎发育过程中在体节和鳃弓分化中表达，在成人组织中是骨骼肌特异性的。作为替代剪接事件的结果，产生了两种VGL-3的异构体。