FITC标记的清道夫受体B1+B2抗体
产品名称： FITC标记的清道夫受体B1+B2抗体
英文名称： Anti-Scavenger Receptor BI + BII/FITC
产品编号： HZ-17277R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
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Rabbit Anti-Scavenger Receptor BI + BII/FITC Conjugated antibody
FITC标记的清道夫受体B1+B2抗体
| 英文名称 | Anti-Scavenger Receptor BI + BII/FITC |
| 中文名称 | FITC标记的清道夫受体B1+B2抗体 |
| 别 名 | 85 kDa lysosomal membrane sialoglycoprotein; CD36 and LIMPII Analogous 1; CD36L1; CD36L2; CLA1; HLGP85; LGP85; LIMP II; Lysosome membrane protein II; MGC138242; SCARB1; SCARB2; Scavenger receptor class B member 2; Scavenger Receptor Class B Type I; SRBI; SRBII. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 心血管 细胞生物 信号转导 细胞膜受体 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 61kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Scavenger Receptor BI + BII |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] Function: High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells. Subcellular Location: Lysosome; lysosomal membrane; multi-pass membrane protein. Database links: Entrez Gene: 949 Human Entrez Gene: 950 Human Entrez Gene: 12492 Mouse Entrez Gene: 20778 Mouse Entrez Gene: 117106 Rat Entrez Gene: 25073 Rat Omim: 601040 Human Omim: 602257 Human SwissProt: Q14108 Human SwissProt: Q8WTV0 Human SwissProt: O35114 Mouse SwissProt: Q61009 Mouse SwissProt: P27615 Rat SwissProt: P97943 Rat Unigene: 298813 Human Unigene: 349656 Human Unigene: 592984 Human Unigene: 282242 Mouse Unigene: 297964 Mouse Unigene: 399507 Mouse Unigene: 410528 Mouse Unigene: 3957 Rat Unigene: 88169 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白是高密度脂蛋白胆固醇（HDL）的质膜受体。编码的蛋白质介导胆固醇转移到HDL和从HDL。此外，该蛋白是丙型肝炎病毒糖蛋白E2的受体。已经发现了两个编码不同亚型的转录本变体。[ RefSeq，MAR 2011 ]