OCT4 Rabbit pAb (APR27816N)
产品名称: OCT4 Rabbit pAb (APR27816N)
英文名称: OCT4 Rabbit pAb (APR27816N)
产品编号: APR27816N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: IHC (HeLa cells, Homo sapiens, Mus musculus) IF (HeLa cells) WB (Homo sapiens, Mus musculus)
分子量:Calculated MW: 30kDa/38kDa Observed MW: 45KDa 细胞定位:Cytoplasm, Nucleus 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 总结:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.