FITC标记的肿瘤/睾丸抗原2.4抗体
产品名称: FITC标记的肿瘤/睾丸抗原2.4抗体
英文名称: Anti-BAGE4/FITC
产品编号: HZ-9116R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-BAGE4/FITC Conjugated antibody
FITC标记的肿瘤/睾丸抗原2.4抗体
产品编号 | bs-9116R-FITC |
英文名称 | Anti-BAGE4/FITC |
中文名称 | FITC标记的肿瘤/睾丸抗原2.4抗体 |
别 名 | B melanoma antigen 4; B melanoma antigen family, member 4; BAGE4; BAGE4_HUMAN; Cancer/testis antigen 2.4; CT2.4; MGC119851; MGC119852; MGC119853; MLL3P. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 2.5kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human BAGE4 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas. Subcellular Location: Secreted Tissue Specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas. Similarity: Belongs to the BAGE family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
一组基因,BAT1-BAT5,已经定位在TNF-α和TNF-β基因的附近。该基因在该簇附近被发现,在120 kb区域中,该基因被定位在C2附近,该基因包括HSP70基因对。这些基因均位于人类主要组织相容性复合体III类区域内。该基因被认为是两个不同的基因,NG36和G9A,彼此相邻,但最近的出版物显示,只有一个单一的基因。该基因编码的蛋白被认为参与细胞内蛋白质-蛋白质相互作用。有三个交替剪接的转录本基因的变体,但只有两个被充分描述。[ RefSeq,JUL 2008 ]提供。