FITC标记的环指蛋白215抗体
产品名称： FITC标记的环指蛋白215抗体
英文名称： Anti-RNF215/FITC
产品编号： HZ-9264R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-RNF215/FITC Conjugated antibody
FITC标记的环指蛋白215抗体
| 产品编号 | bs-9264R-FITC |
| 英文名称 | Anti-RNF215/FITC |
| 中文名称 | FITC标记的环指蛋白215抗体 |
| 别 名 | RING finger protein 215; Rnf215; RN215_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RNF215 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF215 (ring finger protein 215), is a 377 amino acid multi-pass membrane protein containing one RING-type zinc finger. The gene encoding RNF215 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Contains 1 RING-type zinc finger. Database links: Entrez Gene: 200312 Human Entrez Gene: 71673 Mouse SwissProt: Q9Y6U7 Human SwissProt: Q5SPX3 Mouse Unigene: 592194 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
环型锌指基序存在于许多病毒和真核蛋白质中，并且由能够结合两个锌原子的保守的富含半胱氨酸的结构域构成。含有保守结构域的蛋白质一般参与蛋白质降解的泛素化途径。RNF215（环指蛋白215）是一种含有一个环状锌指的377氨基酸多通道膜蛋白。编码RNF215的基因映射到人类第22号染色体，该基因含有500个以上的基因，是第二个最小的人类染色体。映射到22号染色体的几个基因的突变参与了PelLAN McDeMID综合征、2型神经纤维瘤病、孤独症和精神分裂症的发生。