Olr1 (NM_138648) Mouse Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
安诺伦(北京)生物科技有限公司
Olr1 (NM_138648) Mouse Recombinant Protein

Olr1 (NM_138648) Mouse Recombinant Protein

商家询价

产品名称: Olr1 (NM_138648) Mouse Recombinant Protein

英文名称: Olr1 (NM_138648) Mouse Recombinant Protein

产品编号: PM42550M5

产品价格: 0

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: null

安诺伦(北京)生物科技有限公司
  • 联系人 :
  • 地址 : 北京大兴经济技术开发区天骥智谷35A
  • 邮编 :
  • 所在区域 : 北京
  • 电话 : 189****2642 点击查看
  • 传真 : 点击查看
  • 邮箱 : 3359689365@qq.com

产品概述:Purified recombinant protein of Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM55536V], encoding Mouse full-length Olr1.

表达系统:HEK293T

种属:Mouse

标签类型:C-MYC/DDK

分子量:42.1 kDa

通用名:Olr1

总结:Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).[UniProtKB/Swiss-Prot Function]

形式:Liquid

浓度:>50 ug/mL as determined by microplate BCA method

纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

别名:LOX-1; Scare1; SR-EI