血管紧张素II受体样蛋白1抗体
产品名称： 血管紧张素II受体样蛋白1抗体
英文名称： Apelin Receptor
产品编号： 2430
产品价格： null
产品产地： 上海
品牌商标： 雅吉
更新时间： null
使用范围： WB ELISA Flow-Cyt ICC IF
上海雅吉生物科技有限公司
- 联系人 :
- 地址 : 上海市闵行区元江路5500号第1幢5658室
- 邮编 :
- 所在区域 : 上海
- 电话 : 158****3937 点击查看
- 传真 : 点击查看
- 邮箱 : yajikit@163.com
| 中文名称 | 血管紧张素II受体样蛋白1抗体 |
| 别 名 | APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN. |
| 研究领域 | 心血管 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Dog, Rabbit, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq Function: Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. Subcellular Location: Cell membrane. Tissue Specificity: Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P35414 Gene ID: 187 Database links: Entrez Gene: 429337 Chicken Entrez Gene: 615435 Cow Entrez Gene: 187 Human Entrez Gene: 23796 Mouse Entrez Gene: 83518 Rat Omim: 600052 Human SwissProt: P35414 Human SwissProt: Q9WV08 Mouse SwissProt: Q9JHG3 Rat Unigene: 438311 Human Unigene: 29368 Mouse Unigene: 7965 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample:Lane 1: Heart (Mouse) Lysate at 40 ug Lane 2: Heart (Rat) Lysate at 40 ug Lane 3: Cerebrum (Mouse) Lysate at 40 ug Lane 4: Cerebrum (Rat) Lysate at 40 ug Lane 5: Spinal cord (Mouse) Lysate at 40 ug Lane 6: Spinal cord (Rat) Lysate at 40 ug Primary: Anti-Apelin Receptor (bs-2430R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44/58 kD Observed band size: 50 kD  Sample:Stomach (Mouse) Lysate at 40 ug Primary: Anti-Apelin Receptor (bs-2430R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD  Positive control(blue): mouse SplenocytesIsotype Antibody (orenge): Rabbit IgG, Dilution: 1ug in 100 u1 X PBS containing 0.5% BSA Secondary Antibody(light blue): Goat anti-rabbit IgG-FITC,Dilution: 1:200 in 1 X PBS containing 0.5% BSA Primary Antibody catalog number (green): bs-2430R, Dilution: 1ug in 100ul 1X PBS containing 0.5% BSA |