Recombinant Human Liver-Expressed Chemokine/CCL16 (Human LEC/CCL16)
产品名称： Recombinant Human Liver-Expressed Chemokine/CCL16 (Human LEC/CCL16)
英文名称： Recombinant Human Liver-Expressed Chemokine/CCL16 (Human LEC/CCL16)
产品编号： 90962ES08
产品价格： 0
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2023-08-17T13:40:59
使用范围： null
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Product Information
Product Name
Cat#
Size
Price（¥）
Recombinant Human Liver-Expressed Chemokine/CCL16 (Human LEC/CCL16)
90962ES08
5 μg
815.00
90962ES60
100 μg
7865.00
90962ES76
500 μg
20425.00
Product Description
Human CCL16, also called Liver-expressed chemokine (LEC), Monotactin-1 (MTN-1), IL-10-inducible chemokine and so on, is expressed by the CCL16 gene located on the chromosome 17 in humans. The gene encodes a 120 a.a. residue precursor protein with a 23 a.a. residue predicted signal peptide that is cleaved to generate a 97 a.a. residue mature protein. The protein is secreted by the liver, thymus, spleen cells and showing chemotactic activity for lymphocytes and monocytes but it is distantly related to other CC chemokines, exhibiting less than 30 % sequence identity. CCL16 is highly induced by IL-10, IFN-γ and bacterial lipopolysaccharide in monmcytes and signal through CCR1, CCR2, CCR5, and CCR8.
Product Properties
Synonyms
C-C motif chemokine 16, HCC-4, IL-10-inducible chemokine, LCC-1
Accession
O15467
GeneID
Source
E.coli-derived human Liver-Expressed Chemokine Protein, Gln24-Gln2
Molecular Weight
Approximately 11.2 kDa.
AA Sequence
QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 97 % by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220505