LCK (Human) Recombinant Protein
产品名称： LCK (Human) Recombinant Protein
英文名称： LCK (Human) Recombinant Protein
产品编号： P4714
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human LCK (NM_005356, 1 a.a. - 509 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
- Theoretical MW (kDa):
- 92.762
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purification:
- GST affinity chromatography
- Concentration:
- 0.140 ug/uL
- Activity:
- 66 pmol/ug x min
- Storage Buffer:
- In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 3932
- Protein Accession#:
- NM_005356
- Gene Name:
- LCK
- Gene Alias:
- YT16,p56lck,pp58lck
- Gene Description:
- lymphocyte-specific protein tyrosine kinase
- Omim ID:
- 153390
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
- Other Designations:
- T-lymphocyte specific protein tyrosine kinase p56lck,p56(LSTRA) protein-tyrosine kinase,protein tyrosine kinase,proto-oncogene tyrosine-protein kinase LCK
- Interactome
- Related Disease