FITC标记的BCL7B蛋白抗体
产品名称： FITC标记的BCL7B蛋白抗体
英文名称： Anti-BCL7B/FITC
产品编号： HZ-9298R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BCL7B/FITC Conjugated antibody
FITC标记的BCL7B蛋白抗体
| 产品编号 | bs-9298R-FITC |
| 英文名称 | Anti-BCL7B/FITC |
| 中文名称 | FITC标记的BCL7B蛋白抗体 |
| 别 名 | B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; BCL 7B; BCL7B_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCL7B |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome. Function: May play a role in lung tumor development or progression. Tissue Specificity: Ubiquitous. DISEASE: Note=BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. Similarity: Belongs to the BCL7 family. Database links: Entrez Gene: 9275 Human Entrez Gene: 12054 Mouse Omim: 605846 Human SwissProt: Q9BQE9 Human SwissProt: Q921K9 Mouse Unigene: 647051 Human Unigene: 405834 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
BCL7B与BCL7A蛋白具有高度同源性，已知其直接参与Burkt淋巴瘤细胞系中复杂的染色体易位。BC7B的特异功能尚未确定。然而，它可能在肺肿瘤的发展或进展中发挥作用。BCL7B基因位于先天性疾病威廉姆斯综合征中通常缺失的染色体区域。