FITC标记的SAMD8蛋白抗体
产品名称: FITC标记的SAMD8蛋白抗体
英文名称: Anti-SAMD8/FITC
产品编号: HZ-19376R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SAMD8/FITC Conjugated antibody
FITC标记的SAMD8蛋白抗体
英文名称 | Anti-SAMD8/FITC |
中文名称 | FITC标记的SAMD8蛋白抗体 |
别 名 | 1110053F04Rik; 1700010P07Rik; FLJ25082; MGC118303; RP11-487I5.5; SMSr; Sphingomyelin synthase related; Sphingomyelin synthase related protein 1; Sterile alpha motif domain containing 8. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SAMD8 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: SAMD8 is a multi-pass membrane protein. It belongs to the sphingomyelin synthase family and contains 1 SAM (sterile alpha motif) domain. The function of the SAMD8 protein remains unknown. Function: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. Similarity: Belongs to the sphingomyelin synthase family. Database links: Entrez Gene: 142891 Human Entrez Gene: 67630 Mouse Entrez Gene: 305684 Rat Omim: 611575 Human SwissProt: Q96LT4 Human SwissProt: Q9DA37 Mouse SwissProt: Q641X0 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SAMD8是一种多通道膜蛋白。它属于鞘磷脂合成酶家族,包含1个山姆(无菌α基序)结构域。SAMD8蛋白的功能尚不清楚。