FITC标记的原钙粘附蛋白α9抗体
产品名称： FITC标记的原钙粘附蛋白α9抗体
英文名称： Anti-PCDHA9/FITC
产品编号： HZ-11120R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PCDHA9/FITC Conjugated antibody
FITC标记的原钙粘附蛋白α9抗体
| 产品编号 | bs-11120R-FITC |
| 英文名称 | Anti-PCDHA9/FITC |
| 中文名称 | FITC标记的原钙粘附蛋白α9抗体 |
| 别 名 | KIAA0345; PCDH alpha 9; Protocadherin alpha 9; PCDA9_HUMAN; Protocadherin alpha-9; PCDH-alpha-9. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 102kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCDHA6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA9 (protocadherin alpha 9), also known as KIAA0345, is a 950 amino acid single-pass type I membrane protein that contains six cadherin domains and is encoded by a gene which is located within the protocadherin alpha gene cluster on human chromosome 5. Existing as multiple alternatively spliced isoforms, PCDHA9 functions as a potential calcium-dependent cell adhesion protein that may be involved in the establishment and maintenance of neuronal connections within the brain. Function: RelevancePotential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subcellular Location: Cell membrane; Single-pass type I membrane protein Similarity: Contains 6 cadherin domains. Database links: UniProtKB/Swiss-Prot: Q9Y5H5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
原粘蛋白是一大类钙黏蛋白样细胞粘附蛋白，参与脑内神经元连接的建立和维持。共有三个原粘蛋白基因簇，命名为α、β和γ，它们都含有多个排列整齐的基因。PCDHA9（原粘蛋白α9）又称KIAA0345，是一种含有6个钙黏蛋白结构域的950-氨基酸单通道I型膜蛋白，由位于人染色体5的原粘蛋白α基因簇内的基因编码。PCDHA9作为多个交替剪接的异构体存在，作为潜在的钙依赖性细胞粘附蛋白参与脑内神经元连接的建立和维持。