FITC标记的DNA聚合酶α3抗体
产品名称： FITC标记的DNA聚合酶α3抗体
英文名称： Anti-POLD3/FITC
产品编号： HZ-12755R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-POLD3/FITC Conjugated antibody
FITC标记的DNA聚合酶α3抗体
| 英文名称 | Anti-POLD3/FITC |
| 中文名称 | FITC标记的DNA聚合酶α3抗体 |
| 别 名 | DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; DNA polymerase delta, subunit 3; DNA polymerase subunit delta p66; DPOD3_HUMAN; KIAA0039; P66; P68; Pol delta C subunit (p66); Pold3; Polymerase (DNA directed), delta 3; Polymerase (DNA-directed), delta 3, accessory subunit. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human POLD3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012] Function: Required for optimal DNA polymerase delta activity. Subunit: Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA. Subcellular Location: Nucleus. Database links: Entrez Gene: 10714 Human Omim: 611415 Human SwissProt: Q15054 Human Unigene: 82502 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码DNA聚合酶δ的66 kDa亚基。DNA聚合酶δ兼具聚合酶和3’-5’外切酶活性，在DNA复制和修复中起重要作用。该编码蛋白通过与其他亚基和加工辅助因子增殖细胞核抗原（PCNA）的相互作用而调节DNA聚合酶δ的活性。另外，已经观察到该基因的剪接转录变体。〔RefSeq，2012〕