Active EGF全长蛋白质-蛋白质/抗原/多肽-试剂-生物在线
深圳市宇德立生物科技有限公司
Active EGF全长蛋白质

Active EGF全长蛋白质

商家询价

产品名称： Active EGF全长蛋白质

英文名称： Beta urogastrone EGF EGF_HUMAN Epidermal growth factor HOMG4 OTTHUMP00000219721 OTTHUMP00000219722 Pro epidermal growth factor URG Urogastro

产品编号： ab9863

产品价格： 0

产品产地： 英国

品牌商标： abcam

更新时间： null

使用范围： null

深圳市宇德立生物科技有限公司
  • 联系人 :
  • 地址 : 深圳市宝安区西乡宝民二路贤基大厦4E
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  • 所在区域 : 广东
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进入展台

 

  • 性质Recombinant
  • 来源E. coli

技术指标

Our Abpromise guarantee covers the use of ab9863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 形式Lyophilised
  • 补充说明Murine EGF is fully biologically active when compared with standards. The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.
  • 浓度由溶解方法决定 

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product has been formulized from 10mM Sodium phosphate. pH 8.0.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶ADD 500UL WATER

常规信息

  • 别名
    • Beta urogastrone
    • EGF
    • EGF_HUMAN
    see all
  • 功能EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
  • 组织特异性Expressed in kidney, salivary gland, cerebrum and prostate.
  • 疾病相关Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.
  • 序列相似性Contains 9 EGF-like domains.
    Contains 9 LDL-receptor class B repeats.
  • 细胞定位Membrane.