FITC标记的神经肽Y受体4抗体
产品名称： FITC标记的神经肽Y受体4抗体
英文名称： Anti-NPY4R/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NPY4R/FITC Conjugated antibody
FITC标记的神经肽Y受体4抗体
| 产品编号 | bs-11522R-FITC |
| 英文名称 | Anti-NPY4R/FITC |
| 中文名称 | FITC标记的神经肽Y受体4抗体 |
| 别 名 | Neuropeptide Y receptor type 4; Neuropeptide Y receptor Y4; NPY 4R; NPY R4; NPY Y4; NPY Y4 receptor; NPY-Y4 receptor; NPY4 R; NPY4-R; NPY4R; NPY4R_HUMAN; NPYR 4; NPYR4; NPYY 4; NPYY4; NPYY4-R; Y4 receptor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NPY4R 151-250aa |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. Function: NPY4R has been reported to be expressed in bladder, brain, colon, endometrium, heart, lung, nasal mucosa, penis, prostate, skeletal muscle, small intestine, stomach, and vessel. ESTs have been isolated from human colon and head/neck libraries. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 505889 Cow Entrez Gene: 101141797 Gorilla Entrez Gene: 100052105 Horse Entrez Gene: 100996758 Human Entrez Gene: 5540 Human Entrez Gene: 397475 Pig Omim: 601790 Human SwissProt: P50391 Human Unigene: 524719 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
胰腺多肽（PP）、神经肽Y（NPY）和肽YY（PYY）与36种氨基酸有关。已经分离出许多与这些肽相关的结构受体，NPY1-R、NPY2-R、NPY3-R、NPY4-R、NPY5-R和NPY-6 R NPY4-R在包括脑、冠状动脉和回肠在内的多个人类组织中表达。NPY4-R映射到人类染色体10q11.2。从大鼠下丘脑分离的NPY-5R编码456个氨基酸蛋白，其总体身份与已知的Y型受体不到35%。人NPY5-R序列几乎与人NPY1-R序列相反，但与人NPY1-R序列相反。NPY5-R定位于下丘脑室旁核、外侧下丘脑以及与控制摄食行为的作用一致的其他部位。编码NPY5-R的基因定位于人类染色体4q32.2。NPY6R在人的心脏和骨骼肌中大量表达，编码NPY6R的基因定位于人类染色体5q31。