FITC标记的PRA1蛋白抗体
产品名称： FITC标记的PRA1蛋白抗体
英文名称： Anti-PRA1/PRAF1/FITC
产品编号： HZ-19980R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PRA1/PRAF1/FITC Conjugated antibody
FITC标记的PRA1蛋白抗体
| 英文名称 | Anti-PRA1/PRAF1/FITC |
| 中文名称 | FITC标记的PRA1蛋白抗体 |
| 别 名 | PRA1 domain family 1; PRA1 family protein 1; PRAF1; PRAF1_HUMAN; prenylated Rab acceptor 1; Prenylated Rab acceptor protein 1; Rab acceptor 1 (prenylated); RABAC1; YIP3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRA1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. Subunit: Homodimer. Interacts with VAMP2 (synaptobrevin-2), GDI1,and PCLO (By similarity). Interacts specifically with prenylated Rab proteins; strongly with RAB4B, RAB5A and RAB5C, and weakly with RAB4A, RAB6, RAB7A, RAB17 and RAB22. Interacts with NDRG1. Subcellular Location: Cell membrane. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle. According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. Tissue Specificity: Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. DISEASE: In fetal tissues, it is more abundant in kidney and lung. Similarity: Belongs to the PRA1 family. Database links: Entrez Gene: 10567 Human Entrez Gene: 14470 Mouse Entrez Gene: 83583 Rat Omim: 604925 Human SwissProt: Q9UI14 Human SwissProt: Q9Z0S9 Mouse SwissProt: O35394 Rat Unigene: 11417 Human Unigene: 22473 Mouse Unigene: 25604 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
一般的RAB蛋白调节器需要由高尔基复合体形成囊泡。通过调节RAB GTP酶对SNARE复合物的作用，可以控制囊泡的对接和融合。此外，它还抑制了GDI从膜中去除RAB-GTP酶。