KLHDC3抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
KLHDC3抗体

KLHDC3抗体

商家询价

产品名称： KLHDC3抗体

英文名称： KLHDC3Antibody

产品编号： XY13905-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 KLHDC3抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 13905-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 13905-1-AP(KLHDC3 antibody) at dilution of 1:1500
  • 13905-1-AP;human testis tissueImmunohistochemistry of paraffin-embedded human testis tissue slide using 13905-1-AP( KLHDC3 Antibody) at dilution of 1:50 (under 40x lens)
  • 13905-1-AP;PC-3 cellsImmunofluorescent analysis of PC-3 cells using 13905-1-AP( KLHDC3 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in Mouse testis tissue, PC-3 cells, rat testis tissue
Positive IHC detected in Human testis tissue
Positive IF detected in PC-3 cells
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:20-1:200
KLHDC3抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen KLHDC3 fusion protein ag4879 Full name Kelch domain containing 3
Calculated molecular
weight		 382aa,43 kDa Observed molecular 
weight		 50 kDa
GenBank accession 
number		 BC041793 Gene ID (NCBI) 116138
Gene symbol KLHDC3 Synonyms DJ20C7.3, hPEAS, kelch domain containing 3, KLHDC3, PEAS, Protein Peas, RP1 20C7.3
BackgroundKLHDC3抗体

The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 3 (KLHDC3), also designated PEAS, contains 5 Kelch repeats and may be involved in meiotic recombination process. The gene encoding KLHDC3 maps to chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. KLHDC3 protein is mainly expressed in cytoplasm, also found in meiotic chromatin.This antibody specifically reacts with the 55kd KLHDC3 protein.KLHDC3抗体

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