DDR1, Human, 重组蛋白 (aa 21-417, His)
产品名称: DDR1, Human, 重组蛋白 (aa 21-417, His)
英文名称: DDR1 Protein, Human, Recombinant (aa 21-417, His)
产品编号: TMPH-01297
产品价格: 20 μg
产品产地: 美国
品牌商标: TargetMol
更新时间: 2024-05-23T17:34:14
使用范围: null
规格 | 价格 |
1340.00 |
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Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.