FITC标记的淋巴管内皮细胞和血管内皮细胞受体1抗体
产品名称： FITC标记的淋巴管内皮细胞和血管内皮细胞受体1抗体
英文名称： Anti-stabilin1/FITC
产品编号： HZ-7510R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-stabilin1/FITC Conjugated antibod
FITC标记的淋巴管内皮细胞和血管内皮细胞受体1抗体
| 英文名称 | Anti-stabilin1/FITC |
| 中文名称 | FITC标记的淋巴管内皮细胞和血管内皮细胞受体1抗体 |
| 别 名 | CLEVER 1; Common lymphatic endothelial and vascular endothelial receptor 1; Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1; fasciclin egf-like; FEEL 1; FELE 1; FEX1; KIAA0246; MS 1 antigen; STAB1; STAB-1; STAB 1; STAB1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 信号转导 生长因子和激素 血管内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 273kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human stabilin1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. Function: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. Subunit: Interacts with CHID1. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. Similarity: Contains 16 EGF-like domains. Contains 7 FAS1 domains. Contains 2 laminin EGF-like domains. Contains 1 Link domain. Database links: Entrez Gene: 23166 Human Omim: 608560 Human SwissProt: Q9NY15 Human Unigene: 301989 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicatio |
稳定蛋白-1是一种大的跨膜受体蛋白，它可能在血管生成、淋巴细胞归巢、细胞粘附或受体清除中发挥作用。该蛋白含有7个FascICLIN、16个表皮生长因子（EGF）样、2个层粘连蛋白型表皮生长因子样结构域以及C型凝集素样透明质酸结合链模块。蛋白质主要在肝、脾和淋巴结的窦内皮细胞上表达。该受体已被证明为内吞糖配体，如低密度脂蛋白、Gram阳性和革兰氏阴性菌以及晚期糖基化终产物。支持其可能作为清道夫受体的作用，蛋白质迅速循环之间的质膜和早期内体。