EMC4, Human, 重组蛋白 (His)
产品名称: EMC4, Human, 重组蛋白 (His)
英文名称: EMC4 Protein, Human, Recombinant (His)
产品编号: TMPH-01299
产品价格: 20 μg
产品产地: 美国
品牌商标: TargetMol
更新时间: 2024-05-23T17:34:14
使用范围: null
规格 | 价格 |
11000.00 |
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Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).