FITC标记的肿瘤坏死因子受体超家族成员19L抗体
产品名称: FITC标记的肿瘤坏死因子受体超家族成员19L抗体
英文名称: Anti-RELT/TNFRSF19L/FITC
产品编号: HZ-18155R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RELT/TNFRSF19L/FITC Conjugated antibody
FITC标记的肿瘤坏死因子受体超家族成员19L抗体
英文名称 | Anti-RELT/TNFRSF19L/FITC |
中文名称 | FITC标记的肿瘤坏死因子受体超家族成员19L抗体 |
别 名 | Receptor expressed in lymphoid tissues; RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 43kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RELT/TNFRSF19L |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008] Function: TNFRSF19L may be involved in T cell activation by mediation of the NF kappa B pathway. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm Similarity: Belongs to the RELT family. Contains 1 TNFR-Cys repeat Database links: Entrez Gene: 84957 Human Entrez Gene: 320100 Mouse Entrez Gene: 361615 Rat Omim: 611211 Human SwissProt: Q969Z4 Human SwissProt: Q8BX43 Mouse Unigene: 533720 Human Unigene: 40336 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
由该基因编码的蛋白质是TNF受体超家族的成员。这种受体在血液组织中特别丰富。已经证明激活NF-κB通路并选择性地结合TNF受体相关因子1(TRAF1)。该受体能够刺激CD3信号存在下的T细胞增殖,这表明其在免疫应答中的调节作用。已经报道了编码相同蛋白质的该基因的两个交替剪接转录变体。[ RefSeq,JUL 2008 ]