ENrich size exclusion chromatography columns are designed for high-resolution separation of proteins and other biomolecules at fast flow rates.

These chromatography columns contain polymeric resin to separate biomolecules by their size.

ENrich size exclusion columns are available in two particle sizes:

    ENrich SEC 70 10 x 300 mm column (780-1070)  for separating biomolecules in the 500 Da to 70 kDa range
    ENrich SEC 650 10 x 300 mm column (780-1650)  for separating biomolecules in the 5 to 650 kDa range
    Both ENrich columns operate at a maximum pressure of 600 psi

Features and Benefits of ENrich Size Exclusion Chromatography Columns

    Flexible flow rate with different sample viscosities and temperature conditions
    Superior quality, reproducible separations
    Faster flow rates than similar media
    Stable from pH 2 to 12

Applications of ENrich Size Exclusion Chromatography Columns

For purifying biomolecules in a variety of workflows:

    High-resolution separation of biomolecules
    Contaminant removal
    Molecular size analysis
    Purity determination

These size exclusion columns are compatible with organic acids (1 M acetic acid), 8 M urea, 6 M guanidine HCl, chaotropic agents, detergents, salts, and 1 M NaOH. Alcohol, up to 20% v/v, can be used to enhance the solubility of nucleotides and peptides.

This support is completely compatible with all commonly used aqueous buffers.
Related Products

ENrich columns are also available in a prepacked format for performing ion exchange chromatography.

Bio-Rad offers other size exclusion chromatography resins for packing your own columns.
More Information

ENrich columns are ideal for use on the NGC chromatography system or any other medium- to high-pressure chromatography systems.