FITC标记的NK细胞表面抑制性受体CD94抗体
产品名称: FITC标记的NK细胞表面抑制性受体CD94抗体
英文名称: Anti-CD94/FITC
产品编号: HZ-2521R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-CD94/FITC Conjugated antibody
FITC标记的NK细胞表面抑制性受体CD94抗体
英文名称 | Anti-CD94/FITC |
中文名称 | FITC标记的NK细胞表面抑制性受体CD94抗体 |
别 名 | Killer cell lectin-like receptor subfamily D member 1; CD 94; CD94 antigen; KLRD 1; KLRD1; KLRD1 protein; KP 43; KP43; Natural killer cells antigen CD94; NK cell receptor; KLRD1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 免疫学 细胞膜受体 细胞类型标志物 自然杀伤细胞 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 20kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CD94 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]. Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with NKG2 family members. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 3824 Human Omim: 602894 Human SwissProt: Q13241 Human Unigene: 524251 Human Unigene: 562457 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
自然杀伤(NK)细胞是一种独特的淋巴细胞谱系,介导细胞毒活性和分泌细胞因子在免疫刺激。C型凝集素超家族的几个基因,包括NKG2家族成员,都是由NK细胞表达的,可能参与NK细胞功能的调节。KLRD1(CD94)是一种在NK细胞上优先表达的抗原,被归类为II型膜蛋白,因为它具有外部C端。三个转录变体,编码两种不同的异构体已经发现这个基因。[由RefSeq提供]。