FITC标记的前列腺素合成酶PTGIS抗体
产品名称： FITC标记的前列腺素合成酶PTGIS抗体
英文名称： Anti-PTGIS/FITC
产品编号： HZ-19585R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PTGIS/FITC Conjugated antibody
FITC标记的前列腺素合成酶PTGIS抗体
| 英文名称 | Anti-PTGIS/FITC |
| 中文名称 | FITC标记的前列腺素合成酶PTGIS抗体 |
| 别 名 | CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; EC 5.3.99.4; MGC126858; MGC126860; OTTHUMP00000031777; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI; PTGIS; PTGIS_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 心血管 细胞生物 发育生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PTGIS |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008] Function: Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2). Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate. Similarity: Belongs to the cytochrome P450 family. Database links: Entrez Gene: 5740 Human Entrez Gene: 282021 Cow Entrez Gene: 19223 Mouse Entrez Gene: 25527 Rat Omim: 601699 Human SwissProt: Q29626 Cow SwissProt: Q16647 Human SwissProt: O35074 Mouse SwissProt: Q62969 Rat Unigene: 5247 Cow Unigene: 302085 Human Unigene: 2339 Mouse Unigene: 73051 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码细胞色素P450酶家族的一个成员。细胞色素P450蛋白是一氧化酶，催化许多涉及药物代谢和合成胆固醇、类固醇和其他脂质的反应。然而，根据序列相似性而不是功能相似性，该蛋白被认为是细胞色素P450超家族的成员。这种内质网膜蛋白催化前列腺素H2转化为前列环素（前列腺素I2），一种有效的血管扩张剂和血小板聚集抑制剂。前列环素及其生理拮抗剂血栓素A2的失衡导致心肌梗塞、中风和动脉粥样硬化的发展。[ RefSeq，JUL 2008 ]