CCL13 (Human) Recombinant Protein
产品名称: CCL13 (Human) Recombinant Protein
英文名称: CCL13 (Human) Recombinant Protein
产品编号: P4425
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human CCL13 (Q99616) recombinant protein expressed in Escherichia coli.
- Sequence:
- QPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT
- Theoretical MW (kDa):
- 8.5
- Form:
- Lyophilized
- Preparation Method:
- Escherichia coli expression system
- Endotoxin Level:
- < 0.01 ng/ug or < 0.1 EU/ug
- Activity:
- The activity is determined by the ability of MCP-4 to chemoattract human THP-1 cells and is detectable starting at 1 ug/mL.
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with sterilized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue
Lane 1: non-reducing conditions
Lane 2: reducing conditions
- Note:
- Result of activity analysis
-
Human THP-1 cells were allowed to migrate to human CCL13 at (0, 0.1, 1, 10, 100 and 1000 ng/mL). After 45 minutes, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above.
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 6357
- Protein Accession#:
- Q99616
- Gene Name:
- CCL13
- Gene Alias:
- CKb10,MCP-4,MGC17134,NCC-1,NCC1,SCYA13,SCYL1
- Gene Description:
- chemokine (C-C motif) ligand 13
- Omim ID:
- 601391
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq
- Other Designations:
- CK-beta-10,monocyte chemoattractant protein 4,monocyte chemotactic protein 4,new CC chemokine 1,small inducible cytokine A13,small inducible cytokine subfamily A (Cys-Cys), member 13
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Birth Weight
- Bronchiolitis, Viral
- Encephalomyelitis, Autoimmune, Experimental
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- HIV Infections
- Infant, Premature, Diseases
- Leukemia
- Leukemia, Myeloid, Acute
- Meningeal Neoplasms
- Meningioma
- Multiple Sclerosis
- Ovarian Neoplasms
- Respiratory Syncytial Virus Infections