GYPB Rabbit pAb (APR21610N)
产品名称: GYPB Rabbit pAb (APR21610N)
英文名称: GYPB Rabbit pAb (APR21610N)
产品编号: APR21610N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 6kDa/9kDa 细胞定位:Cell membrane, Single-pass type I membrane protein 稀释方法:IF 1:50 - 1:200 总结:Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.