PTPN18 (N-term) Peptide
产品名称： PTPN18 (N-term) Peptide
英文名称： PTPN18 (N-term) Peptide
产品编号： P3234
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTPN18.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PTPN18.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Characterization of the PEST family protein tyrosine phosphatase BDP1.
Kim YW, Wang H, Sures I, Lammers R, Martell KJ, Ullrich A.Oncogene. 1996 Nov 21;13(10):2275-9.
- Entrez GeneID:
- 26469
- Protein Accession#:
- Q99952
- Gene Name:
- PTPN18
- Gene Alias:
- BDP1,PTP-HSCF
- Gene Description:
- protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
- Omim ID:
- 606587
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- brain-derived phosphatase,protein tyrosine phosphatase, non-receptor type 18