分子量：Calculated MW: 116kDa/133kDa
Observed MW: 180KDa

细胞定位：Membrane, Single-pass type I membrane protein

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein.  Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch.  Mutations that alter the jagged 1 protein cause Alagille syndrome.  Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.