分子量：Calculated MW: 95kDa/109kDa/110kDa
Observed MW: 110kDa

细胞定位：Endoplasmic reticulum membrane, Multi-pass membrane protein, Sarcoplasmic reticulum membrane

稀释方法：WB 1:200 - 1:1000

总结：This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.