[KO Validated] AKT2 Rabbit pAb (AMM08802N)
产品名称: [KO Validated] AKT2 Rabbit pAb (AMM08802N)
英文名称: [KO Validated] AKT2 Rabbit pAb (AMM08802N)
产品编号: AMM08802N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 51kDa/55kDa Observed MW: 60kDa 细胞定位:Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:100 ICC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50 ChIP 1:20 - 1:100 总结:This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.