重组人PPP1R14A

中文名称：重组人PPP1R14A
英文名称：Recombinant Human Protein Phosphatase 1 Regulatory Subunit 14A
产品规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Pro147在C端含有His标签。

PPP1R14A质量控制：＞95%(还原性SDS-PAGE)

PPP1R14A制剂：液体

PPP1R14A保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PPP1R14A：
Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. In addition, inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration. 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！