Anti-GHRL Polyclonal Antibody

品牌：solarbio | 货号：K002617P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002617P-50ul	solarbio	50ul	960.00元
K002617P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-GHRL Polyclonal Antibody
别名	MTLRP
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Rat
蛋白分子量	13kDa
Gene ID	51738
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human GHRL
性状	液体
Public Immunogen Range	Recombinant protein of human GHRL
Subcellular Locations	Secreted
Swiss Prot	Q9UBU3
克隆类型	Polyclonal Antibody
背景资料	This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.