SENP1 (N-term) Peptide
产品名称： SENP1 (N-term) Peptide
英文名称： SENP1 (N-term) Peptide
产品编号： P0294
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SENP1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SENP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Herpes simplex virus 1 ICP0 co-localizes with a SUMO-specific protease.
Bailey D, O'Hare P.J Gen Virol. 2002 Dec;83(Pt 12):2951-64.
- 2.
- Differential regulation of sentrinized proteins by a novel sentrin-specific protease.
Gong L, Millas S, Maul GG, Yeh ET.J Biol Chem. 2000 Feb 4;275(5):3355-9.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of SENP1 polyclonal antibody (Cat # PAB2411) in whole HL-60 cell lysate : SENP1 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SENP1 polyclonal antibody (Cat # PAB2411) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 29843
- Protein Accession#:
- NP_055369;Q9P0U3
- Gene Name:
- SENP1
- Gene Alias:
- SuPr-2
- Gene Description:
- SUMO1/sentrin specific peptidase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]).[supplied by OMIM
- Other Designations:
- SUMO1/sentrin specific protease 1,sentrin/SUMO-specific protease,sentrin/SUMO-specific protease 1